For painful HIV-neuropathy, we found two research (801 individuals). We included eight research, involving 2488 contributors, two more studies and 415 more individuals than the earlier version of this review. Two studies used a placebo control and 6 used 0.04% topical capsaicin as an 'lively' placebo to help maintain blinding. Eight research happy our inclusion criteria, together with two new research for this replace. Two review authors independently searched for research, extracted efficacy and adverse occasion data, and examined issues of study high quality and potential bias. At both eight and 12 weeks about 10% extra individuals reported themselves much or very much improved with excessive-concentration capsaicin than with 'energetic' placebo